Dr Shabbir Moochhala
BSC (HONS) MBCHB PHD FRCP (EDIN)
About Dr Shabbir Moochhala
Dr Shabbir Moochhala is a consultant Nephrologist and Physician at the Royal Free Hospital. He has eight years experience of consultant practice at the Royal Free covering all aspects of kidney disease, including acute kidney injury, glomerulonephritis, hypertension, transplantation and all forms of dialysis.
Dr Moochhala is one of very few nephrologists in specialist centres who also maintains a general medical practice. This means that he is consulted by patients with a wide variety of medical and kidney problems. Dr Moochhala also sees patients with multi-system problems or where the specialty is unclear. He always tries to address all of his patients’ medical issues and not just the kidney ones.
He is Principal Investigator at the Royal Free for a number of international medical trials on rare kidney stone disease. He specialises in the diagnosis and management of rare stone-forming conditions, renal tubular and electrolyte disorders, hypertensive disorders and Fabry disease. Of course, to be able to detect and treat rare diseases, an excellent knowledge of common diseases is also required, and Dr Moochhala has wide experience of general medicine and renal medicine over eight years of consultant practice in north London.
He has specialist expertise in the prevention of recurrent kidney stones, and runs the largest medical kidney stone clinic in the UK, based at the Royal Free. Dr Moochhala can help patients who form stones by using specialised medical tests to find out the cause, which can then allow preventative treatments.
He also performs ultrasound-guided renal biopsies and is a trainer for this procedure.
- General Medicine
- All aspects of nephrology and general medicine
- Renal stones
- Fluid and electrolyte disorders
- Kidney stone formers
- Rare kidney diseases
- Renal tubular disease
- Fabry nephropathy
- Diagnostic kidney biopsy
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Dr Moochhala’s PhD research focused on the mechanisms of formation of calcium renal stones. Since then, he has published scientific papers, participated in interventional clinical trials, led teams collecting physiological and genetic information from patients with their consent and collaborated with leading kidney stone research groups internationally. He is active at national level, having set up a national stone disease registry, sat as physician expert on a NICE guidelines committee, and organised national information days for patients and their families.
- Oomatia A, Dupont P, Bass P, Moochhala S. Shining a light on an unusual case of chronic kidney disease. Kidney Int. 2018 Apr;93(4):1023-1024.
- Oates T, Moochhala S. Recognition and management of acute kidney injury. Prescriber (2017) 28 (4) 17-21.
- Hoppe B, Niaudet P, Salomon R, Harambat J, Hulton SA, Van’t Hoff W, Moochhala SH, Deschênes G, Lindner E, Sjögren A, Cochat P. A randomised Phase I/II trial to evaluate the efficacy and safety of orally administered Oxalobacter formigenes to treat primary hyperoxaluria. Pediatr Nephrol. 2017 May;32(5):781-790. doi: 10.1007/s00467-016-3553-8. Epub 2016 Dec 6.
- Oliver KV, Vilasi A, Maréchal A, Moochhala SH, Unwin RJ, Rich PR. Infrared vibrational spectroscopy: a rapid and novel diagnostic and monitoring tool for cystinuria. Sci Rep. 2016 Oct 10;6:34737. doi: 10.1038/srep34737.
- Shavit L, Chen L, Ahmed F, Ferraro PM, Moochhala S, Walsh SB, Unwin R. Selective screening for distal renal tubular acidosis in recurrent kidney stone formers: initial experience and comparison of the simultaneous furosemide and fludrocortisone test with the short ammonium chloride test. Nephrol Dial Transplant (2016) doi: 10.1093/ndt/gfv423 First published online: March 8, 2016
- Oliver, K. V., Matjiu, F., Davey, C., Moochhala, S., Unwin, R. J., & Rich, P. R. Attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy as a bedside diagnostic tool for detecting renal disease biomarkers in fresh urine samples. Progress in Biomedical Optics and Imaging – Proceedings of SPIE (2015) 9332.
- Shavit, L., Girfoglio, D., Vijay, V., Goldsmith, D., Ferraro, P. M., Moochhala, S. H., & Unwin, R. Vascular Calcification and Bone Mineral Density in Recurrent Kidney Stone Formers. Clin J Am Soc Nephrol. (2015) 10: 278-285.
- Shavit, L., Ferraro, P. M., Johri, N., Robertson, W., Walsh, S. B., Moochhala, S., & Unwin, R. Effect of being overweight on urinary metabolic risk factors for kidney stone formation. Nephrol Dial Transplant (2015) 30: 607-613.
- Moochhala SH (2012). Extracellular pyrophosphate in the kidney: How does it get there and what does it do? Nephron Physiol 120, 33-38.
- Sayer JA, Moochhala SH, Thomas DJ (2010). The medical management of urolithiasis. Br J Med Surg Urol 3, 87-95.
- Carr G, Moochhala SH, Eley L, Vandewalle A, Simmons NL, Sayer JA (2009). The pyrophosphate transporter ANKH is expressed in kidney and bone cells and colocalises to the primary cilium / basal body complex. Cell Physiol Biochem 24, 595-604.
- Eley L, Moochhala SH, Simms R, Hildebrandt F, Sayer JA (2008). Nephrocystin-1 interacts directly with Ack1 and is expressed in human collecting duct. Biochem Biophys Res Commun. 371 (4), 877-82.
- Moochhala SH, Sayer JA, Carr G, Simmons NL (2008). Renal calcium stones: insights from the control of bone mineralization. Exp Physiol 93 (1), 43-9.
- Moochhala S, Unwin R. Electrolytes and acid–base: common fluid and electrolyte disorders. Medicine (Elsevier) July 2015, Volume 43, Issue 7, Pages 374–380.
- Moochhala SH, Unwin RJ (2014). Renal Stone Disease. In: Practical Nephrology, pub by Springer. Chapter 36, pp. 413-428. ISBN 978-1-4471-5546-1
- Sayer JA, Carr G, Moochhala SH, Simmons NL (2008). Pyrophosphate Transport and Stones. In: Proc 2nd Intl Urolithiasis Res Symp, Eds. Evan AP, Lingeman JE, McAteer JA, Williams JC. Pub. by Amer. Institute of Physics, Melville, NY, pp. 71-80.